WHI-P258 - CAS# 21561-09-1 60187 75 nM and 18 nM

75 nM and 18 nM in SupT1 cells

but not in the WT cells at any concentrations

Molecular Weight: 353

SJ000291942 causes an increase in bmp2b and szl expression

potent and selective inhibitor of glycogen synthase kinase 3β (GSK3β) with an IC50 ~7 nM

WHI-P258 - CAS# 21561-09-1 60187 75 nM and 18 nMWHI P258, CAS No. 21561 09 1, is a Janus kinase 3 inhibitor. WHI P131 may provide the basis for the design of new treatment strategies against acute lymphoblastic leukemia, the most common form of childhood cancer. Product information CAS Number: 21561 09 1 Molecular Weight: 281. 31 Formula: C16H15N3O2 Synonym: WHI P258 WHI P 258 WHIP 258 WHI P 258 Chemical Name: 6,7 Dimethoxy N phenylquinazolin 4 amine Smiles: COC1=CC2=NC=NC(NC3C=CC=CC=3)=C2C=C1OC