CU-3 aflumizone Smiles: O[C@H]1[C@H]2O[C@H]2[C@H](O)[C@@H](O)[C@@H]1O

Smiles: O[C@H]1[C@H]2O[C@H]2[C@H](O)[C@@H](O)[C@@H]1O

CAS Number: 38183-12-9

a selective endothelin ET(B) receptor antagonist

AD57 potently dampened the pathway-related human kinases B-Raf

InChiKey: XTKLTGBKIDQGQL-UHFFFAOYSA-N

CU-3 aflumizone Smiles: O[C@H]1[C@H]2O[C@H]2[C@H](O)[C@@H](O)[C@@H]1OCU 3 is the racemate of (5Z,2E) CU 3. (5Z,2E) CU 3 is a potent and selective inhibitor against the isozyme of DGK with an IC50 value of 0. 6 M, competitively inhibits the affinity of DGK for ATP with a Km value of 0. 48 mM. (5Z,2E) CU 3 targets the catalytic region, but not the regulatory region of DGK. (5Z,2E) CU 3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells. Product information CAS