ARS-853 Size:Contact [email protected] for quotation 38)30-23-7-5-4-6-21(23)19-8-10-20(11-9-19)25(34)32-14-12-27(36

38)30-23-7-5-4-6-21(23)19-8-10-20(11-9-19)25(34)32-14-12-27(36

is an orally bioavailable small molecule with potential antineoplastic activity

Chemical Name: 6-hydroxy-2-phenyl-4H-chromen-4-one

The MIC50 and MIC90 values for BTZ043 are 0

Epub 2014 Jul 9

ARS-853 Size:Contact [email protected] for quotation 38)30-23-7-5-4-6-21(23)19-8-10-20(11-9-19)25(34)32-14-12-27(36ARS 853 is a cell active, selective, covalent KRAS G12C inhibitor with an IC50 of 2. 5 M. ARS 853 inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. Product information CAS Number: 1629268 00 3 Molecular Weight: 432. 94 Formula: C22H29ClN4O3 Chemical Name: 1 {3 [4 (2 {[4 chloro 2 hydroxy 5 (1 methylcyclopropyl)phenyl]amino}acetyl)piperazin 1 yl]azetidin 1 yl}prop 2 en 1 one Smiles: