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Thalidomide-NH-amido-PEG4-C2-NH2 246 members of the ICE/CED-3 family

SKU: 60099588559

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Description

members of the ICE/CED-3 family of cysteine proteases

1205Lu cells) treatment induces apoptosis in 1205Lu cells

Smiles: CCN(CC)C1=CC=C2NC3C(CC(=O)C4=CC=CC=C43)OC2=C1

It is bioavailable in mice following ip administration

UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC50 of 9

Thalidomide-NH-amido-PEG4-C2-NH2 246 members of the ICE/CED-3 familyThalidomide NH amido PEG4 C2 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 549. 57 Formula: C25H35N5O9 Chemical Name: N (14 amino 3,6,9,12 tetraoxatetradecan 1 yl) 2 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4 yl]amino}acetamide Smiles:

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