Kif15-IN-1 mesylate Examination of the relative potency

Examination of the relative potency of these antagonists in the Early Phase of operant testing (5-15 min post-antagonist) revealed an even greater 100-fold potency difference between naloxone and 6-alpha-naloxol

2018 Jan 20

Pharmacodynamics

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InChiKey: NETXMUIMUZJUTB-UHFFFAOYSA-N

Kif15-IN-1 mesylate Examination of the relative potencyKIF15 IN 1 is a potent inhibitor of KIF15, which pairs with Eg5 inhibitors synergistically to reduce cancer cell growth. Product information CAS Number: 672926 32 8 Molecular Weight: 430. 48 Formula: C20H22N4O5S Chemical Name: ethyl 2 [(2S) 2 (2,4 dioxo 1,2,3,4 tetrahydroquinazolin 3 yl) 3 methylbutanamido] 4 methyl 1,3 thiazole 5 carboxylate Smiles: CC1N=C(NC(=O)[C@H](C(C)C)N2C(=O)C3=CC=CC=C3NC2=O)SC=1C(=O)OCC InChiKey: CTQQKICGMSZCJL AWEZNQCLSA N