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MAC glucuronide linker-2 g hormone human acetate salt (LHRH) InChi: InChI=1S/C70H104N12O14S/c1-14-45(8)61(53(94-12)40-57(86)81-37-22-26-52(81)62(95-13)46(9)63(87)76-51(67-72-35-38-97-67)39-47-23-17-15-18-24-47)79(10)68(91)59(43(4)5)78-66(90)60(44(6)7)80(11)70(93)96-41-48-28-30-49(31-29-48)74-64(88)50(25-21-34-73-69(71)92)75-65(89)58(42(2)3)77-54(83)27-19-16-20-36-82-55(84)32-33-56(82)85/h15

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Description

InChi: InChI=1S/C70H104N12O14S/c1-14-45(8)61(53(94-12)40-57(86)81-37-22-26-52(81)62(95-13)46(9)63(87)76-51(67-72-35-38-97-67)39-47-23-17-15-18-24-47)79(10)68(91)59(43(4)5)78-66(90)60(44(6)7)80(11)70(93)96-41-48-28-30-49(31-29-48)74-64(88)50(25-21-34-73-69(71)92)75-65(89)58(42(2)3)77-54(83)27-19-16-20-36-82-55(84)32-33-56(82)85/h15

24 h) inhibits expression of CCND1 and c-Myc

human PHD3 and monkey PHD2 with IC50 of 18 nM

3-b]quinolin-8-ol

PNU-120596 induces a profound retardation of the kinetics of desensitization

MAC glucuronide linker-2 g hormone human acetate salt (LHRH) InChi: InChI=1S/C70H104N12O14S/c1-14-45(8)61(53(94-12)40-57(86)81-37-22-26-52(81)62(95-13)46(9)63(87)76-51(67-72-35-38-97-67)39-47-23-17-15-18-24-47)79(10)68(91)59(43(4)5)78-66(90)60(44(6)7)80(11)70(93)96-41-48-28-30-49(31-29-48)74-64(88)50(25-21-34-73-69(71)92)75-65(89)58(42(2)3)77-54(83)27-19-16-20-36-82-55(84)32-33-56(82)85/h15MAC glucuronide linker 2 is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 229977 57 5 Molecular Weight: 455. 41 Formula: C20H25NO11 Chemical Name: methyl (2S,3S,4S,5R,6S) 3,4,5 tris(acetyloxy) 6 [2 amino 4 (hydroxymethyl)phenoxy]oxane 2 carboxylate Smiles: COC(=O)[C@H]1O[C@@H](OC2=CC=C(CO)C=C2N)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O InChiKey: ZAZPQJAJSIUIEY KVIJGQROSA N InChi:

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