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PROTAC CRABP-II Degrader-1 x (E1210) Smiles: O=C(CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NC1=CC=C(CCC(=O)N2CCC2=O)C=C1

SKU: 56809833507

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Description

Smiles: O=C(CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NC1=CC=C(CCC(=O)N2CCC2=O)C=C1

pomalidomide appears to inhibit TNF-alpha production

It inhibits PHD2 via binding to the 2OG binding site

PubMed Central PMCID: PMC4573555

Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A

PROTAC CRABP-II Degrader-1 x (E1210) Smiles: O=C(CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NC1=CC=C(CCC(=O)N2CCC2=O)C=C1PROTAC CRABP II Degrader 1 is a potent cellular retinoic acid binding protein (CRABP II) degrader based on cIAp1. Product information CAS Number: 1225383 40 3 Molecular Weight: 764. 95 Formula: C42H60N4O9 Chemical Name: (2E, 4E, 6E) 9 [(3E) 3 [({[2 (2 {[(2S) 2 [(2S, 3R) 3 amino 2 hydroxy 4 phenylbutanamido] 4 methylpentanoyl]oxy}ethoxy)ethyl]carbamoyl}methoxy)imino] 2, 6, 6 trimethylcyclohex 1 en 1 yl] 3, 7 dimethylnona 2, 4, 6, 8 tetraenoic acid

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