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male HBV transgenic mice) treatment markedly suppresses the level of HBV DNA and 3
CAS Number: 5588-20-5
5 mg/mL (14
TH287 could act as a chemotherapeutic agent for cancer research
Molecular Weight: 565
ALK5 Inhibitor II (hydrochloride) Catalog No.:M23387-C male HBV transgenic mice) treatmentIC50: 4, 18, and 23 nM for ALK5 autophosphorylation, TGF cellular assay, and ALK5 binding in HepG2 cells, respectively ALK5 Inhibitor II is an ALK5 inhibitor. The TGF beta family of cytokines signal via serine threonine kinase transmembrane type I and type II receptors. Binding TGF beta1 to the receptor complex triggers activation of activin receptor like kinase (ALK), initiating downstream signaling involving Smad transcription factors, mitogen
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