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ALK-IN-12 danziolide A CN1CCC2=C(Cl)C=CC=C2CC1

SKU: 12171038310

4.8
USD100.00 USD131.00

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Description

CN1CCC2=C(Cl)C=CC=C2CC1

Bunaphtide

InChi: InChI=1S/C25H27FN6O4/c1-14(2)36-16-5-6-18(26)17(10-16)19-12-29-23(27)22(30-19)24(33)31-20-11-28-8-7-21(20)32-9-3-4-15(13-32)25(34)35/h5-8

5)19(26)21(13

SAR407899 (1-3 mg/kg

ALK-IN-12 danziolide A CN1CCC2=C(Cl)C=CC=C2CC1ALK IN 12 is a potent and orally active ALK inhibitor with an IC50 of 0. 18 nM. ALK IN 12 also inhibits IGF1R and InsR (IC50=20. 3 and 90. 6 nM). Antitumor activities. Product information CAS Number: 1197958 53 4 Molecular Weight: 500. 96 Formula: C24H30ClN6O2P Chemical Name: 5 chloro N4 [2 (dimethylphosphoryl)phenyl] N2 [2 methoxy 4 (4 methylpiperazin 1 yl)phenyl]pyrimidine 2, 4 diamine Smiles:

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