PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC
2ClH/c21-17-4-2-1-3-15(17)11-14-7-9-24(10-8-14)13-20-22-18-6-5-16(25)12-19(18)23-20
Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC
Smiles: COC1C=CC(=CC=1)OCC1C2=CC(OC)=C(C=C2CCN1C(=O)C1=CC(Cl)=CC=C1)OC
Consistent with the downregulation of the phosphorylation of FLT3
Bestatin Methyl Ester Catalog No.:M23471-C PROTAC K-Ras Degrader-1 (Compound 518)Product information CAS Number: 65322 89 6 Molecular Weight: 322. 40 Formula: C17H26N2O4 Chemical Name: (2S) 2 [[(2S,3R) 3 amino 2 hydroxy 4 phenylbutanoyl]amino] 4 methylpentanoate Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1C=CC=CC=1)C(=O)OC InChiKey: WGNKTWBIPBOGLO ILXRZTDVSA N InChi: InChI=1S C17H26N2O4 c1 11(2)9 14(17(22)23 3)19 16(21)15(20)13(18)10 12 7 5 4 6 8 12 h4 8,11,13 15,20H,9 10,18H2,1 3H3,(H,19,21) t13 ,14+,15+ m1 s1 Technical Data